DNA Factor II (prothrombin) Mutation
| Profile or Test Panel |
Thrombosis Genetic Risk Profile
|
| Also Known as (Alias) | Factor II genotyping |
| Method | polymerase chain reaction (PCR) based |
| Test Information | Patients testing positive for APC resistance or the Factor V Leiden mutation should be considered for testing for the Factor II (Prothrombin) G20210A variant. Individuals who are homozygous or heterozygous for the 20210A genotype have a 3-to 5-fold elevated risk for venous thrombosis. |
| Additional Test Information | Test Values: Homozygous normal (20210G) Heterozygous or Homozygous abnormal (20210A) *Note abnormal tests are confirmed by repeating tests. |
| Sample Requirements | EDTA (lavender top) |
| Requested Volume | 5cc EDTA (lavender top) tube |
| Minimum Volume or Pediatric volume | 5cc EDTA (lavender top) tube |
| Shipping Information | Whole blood shipped at ambient temperature and should arrive in the lab within 48 hours.
Send samples to: |
| Requisition Form | Request for Testing Hemostasis Reference Laboratory |
| Transaction Code | 3250-04 |
| CPT Codes | 81240 |
| Test Schedule | Weekly on Tuesdays on samples received Wednesday through Monday noon |
| Turn around Time (analytic time) | 3 business days |
| Report/Results | Fax number required to receive report |